Yes of course this is possible.
Providing your mouth is large enough a standard 55g bag containing 50 skittles can be accommodated easily in the oral cavity.
Once your mouth is full, chew very quickly or lie on your back to avoid the onset of dribbling. The latter may cause you to choke and asphyxiate so take care.
As with most things though, practice makes perfect, so on your first attempt you may wish to manufacture some kind of “dribble guard” from a plastic cup to avoid excessive soilage of your chin and clothes.
Good luck Witter and let us know how you progress with this extremely worthwhile task!